Uniform sarcomere shortening behavior in isolated cardiac muscle cells.
نویسندگان
چکیده
منابع مشابه
Uniform sarcomere shortening behavior in isolated cardiac muscle cells
We have observed the dynamics of sarcomere shortening and the diffracting action of single, functionally intact, unattached cardiac muscle cells enzymatically isolated from the ventricular tissue of adult rats. Sarcomere length was measured either (a) continuously by a light diffraction method or (b) by direct inspection of the cell's striated image as recorded on videotape or by cinemicroscopy...
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Several recent reports have indicated that catecholamines may act directly on the crossbridge cycle, independent of intracellular calcium concentration changes. The present study investigated the effect of isoproterenol on peak force during twitches at constant sarcomere length and unloaded velocity of sarcomere shortening in isolated right ventricular trabeculae of hearts with V, or V3 isomyos...
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Recent experiments using laser diffraction techniques to determine the time course and extent of sarcomere shortening in thin bundles of cardial tissue have given results which suggest that the velocity of sarcomere shortening in cardiac muscle is independent of the developed force (Nassar et al., 1974; Krueger and Pollack, 1975). However, the anatomical complexity of the intact tissue preclude...
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We studied sarcomere performance in single isolated intact cardiac cells using techniques that allow direct measurement of sarcomere length and force. This investigation dealt primarily with sarcomere performance during twitch contractions under lightly loaded conditions. In such contractions, there was a significant portion of the contraction in which sarcomere shortening occurred at constant ...
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during isometric contraction. J Physiol (Lond) 251: 627-643 Krueger JW, Wittenberg BA (1978) Dynamics of myofilament sliding in single intact cardiac muscle cells (abstr). Circulation 58: (suppl II): 33 Lapicque L (1907) Recherches quantitative sur l'excitation electriquer des nerfs traitee comme une polarisation. J Physiol (Paris) 9: 620-635 Manring A, Nassar R, Johnson EA (1977) Light diffrac...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1980
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.76.5.587